There is barely any experience that can be as soothing as getting a full body massage in a dimly lit room and with soft melodious music playing. It is the perfect definition of tranquility and bliss. This is why many people who understand the need for peace of mind and tranquility are booking more massage sessions these days.

Another fantastic thing about body massage that people often do not realize is that it goes beyond offering you total relaxation and peace of mind to trigger other crucial functions that will benefit different aspects of your body system and your mind. A massage can facilitate your nervous system, activate your muscles, and stimulate your organs and glands to produce and release essential body hormones and chemicals to ensure better body health and functionalities for you.

If you are yet to cultivate the habit of booking frequent massages, then you are missing out on a lot of goodies your body could be enjoying now. This article will discuss some of these benefits and why you should not continue missing them. Read on to discover more.

A Body Massage Helps to Relax Your Nervous System

As your body relaxes during a massage session, your nervous system will enter a “rest and digest” mode. Often, when people experience pains and pressure in their body, it is because of nerve pressures that are caused by tight muscles. Booking a fulfilling massage session can help you to relieve this pressure.

A relaxed nervous system will help to balance out your body’s hormone production levels. This means that the production of stress hormones like corticosteroids (LDL) will reduce as relaxation hormones like endorphins increase in your body. Moreover, hormones that regulate body functions like menstrual cycles, sleep/wake cycles, blood sugar, immune cells, and even your digestive system all positively react to the relaxation that full-body massages offer.

Body Massages Help to Refresh Your Skin

The use of massage lotions and oil, when combined with the slight friction of the masseuse’s hands on your body, can lead to gentle skin exfoliation. Of course, this will allow new skin cells to grow around your body and help you to achieve better and clearer skin structures.

Body Massages Deliver Musculoskeletal Benefits

The human muscles function like a sponge – they squeeze out blood and lymph fluid when contracted and allow fresh blood to enter when they are relaxed. This means that their real action will bring more fresh oxygen, nutrients, and immune cells to your system.

An experienced massage therapist can also initiate stretching of the muscles and other motion movements to their routines to mobilize the joints and focus beneficial tension on your ligaments, tendons, and muscles.

Body Massages Enhance Supply of Blood to the Bone

Many people do not know that their bones have a blood supply and that an efficient massage therapy session can enhance this supply’s function. Blood helps to bring calcium and other mineral types to the human bones. This is to support the bone’s strength and functionalities.

Indeed, a massage session can improve blood supply to your bones, thereby making them stronger and healthier for better functionalities.

Conclusion

It is established that an efficient massage session can contribute significantly to relaxing your body and giving you the peace of mind you deserve. However, its benefits do not end there. Body massages can also deliver some other health benefits to enthusiasts. This article has discussed the top vital things you should know about the therapy.

Gold Coast Massage therapy supports the spinal care that Chiropractic offers by working the supporting soft tissue, muscle, ligaments and tendons. Book now!

To practise Weighted Dips at home demands tons of equipment’s such as Dip Machines, Dip Stations, Dip Stands and Dip Parallel Bars etc., along with additional weights such as Weighted Plates and Weighted Dip Belts. Although you can purchase all these equipment’s online it would be wiser to practise it at Gym under supervision and lot fewer expenses. And not to mention, the trainer would be able to advise you on your upper body strength and whether you should try Weighted Dips or not. However, if you still want to try Weighted Dips then you can purchase Small Dips Station which can also be used to practise Chest Dips as well. Below are the steps and instructions that you need to follow to perform Weighted Dips:

-Grab your weight belt and wrap it around your waist with your desire weight attached to it by a chain.

-Once you are done with your weight belt, hold on to the bars of Dipping Station and start lifting yourself in an upward direction with your arms straight and your legs crossed.

– Make sure that your elbows are bent in 90 degrees, your neck and trunk are in perfect and straight alignment as well as your eyes are set straight throughout the practice.

– Now once you have lifted yourself, hold on to the instructed position for about 10 seconds or so then return to the original position gradually and slowly. Once you get hang of the whole process, try to practise Weighted Dips 2-3 sets.

However, make sure that before you jump off to Weighted Dips, practise Chest Dips daily and make it a habit before doing Weighted Dips. Also, while you are practising Weighted Dips, make sure that you are comfortable with your position. For always remember that Weighted Dips are evolved and complicated form of Chest Dips and so need a good body posture and strength as a foundation. Hence, try to avoid it if you are at all uncomfortable with your position and don’t take any kind of pain as cramps or lightly. Instead get yourself checked properly of risk of injury is too much if not practised in an instructed manner or posture defectiveness.

• Weighted Dips and Bench Press:
Although Weighted Dips are quite complex work-out options, the same can be said for Bench Press as well. You may call Bench Press as an alternative or variation of Weighted Dips as well. For Bench Press also emphasises on your Sternums, Triceps, Arms and Shoulders muscles. Not only that but it also requires a lot fewer pieces of equipment than Weighted Dips. However, Bench Press is much more effective and helpful for the restoration of your muscles. And is recommended for Muscle-loss post 40 years. Pieces of equipment required to perform Bench Press are Weight Bench, Smith Machine, Barbells or Dumbbells. So, below is a step-by-step instruction on how to practise Bench Press:

– Now slowly lie down with your back facing the Bench, beneath the rack holding the weights (Dumbbell/ Barbells) above them.

– Make sure that your knees are horizontal with your foot spread apart and wide, firmly attached to the ground.

– Now slowly try to grab the bar from the rack with an overhand grip. Make sure that your upper arms are at 45 degrees, your Shoulders and arms wide apart.

– Once you have taken the instructed position, take the bar and lift it in an upward direction, like that towards the ceiling. And bring it near your breastbones. Also make sure that while doing so, your foot is firmly attached to the ground. Pause in that position for a few seconds or so, say 10 seconds and return to your original position.

– Also, while you are doing so, make sure you concentrate on the ceiling rather than the bar to keep your position uptight. Else you might get nervous and injure yourself. Repeat the whole process for a couple of times or as desired.

Make sure that you abide by these guidelines at all cost or it won’t be long to have a broken chest and rib cages at the very least. Bench Press is a very heavy and overwhelming exercise to be very specific and a small err in your posture or your concentration can cost you big time and money. So, it’s always better to be sure of your physique before you go for one. Just like Weighted Dips, Bench Press also requires adequate upper body strength, undivided focus & concentration and arm strength. So, before you jump off to Bench Press, be sure to do in this series instead. Chest Dips, then Weighted Dips and lastly Bench Press. One exercise at a time! And instead of trying all these stunts by yourself at home, consult a trainer first who can evaluate your strength and weakness for these exercises are surely not a charity that will begin with you at home trying all this unsupervised stuffs by yourself.

An antibody conjugate consists of a monoclonal antibody (or fragment thereof), a chemical linker, and a biologically active cytotoxic payload or drug. The selection of conjugated molecules depends on the research purpose and the conjugation method.

Distinguished by different starting materials, crosslinkers, fusion portions, etc., three main classes of the bsAb conjugates are developed for scientific and clinical research.

Antibody-Antibody Conjugates
Antibody-Peptide Conjugates
Antibody-Functionality Conjugates
Antibody-Antibody Conjugates

Antibody-antibody conjugates are generated by conjugating two different whole antibodies together to get a 300kDa bispecific molecule that has the bivalent binding capability for each antigen.

Creative Biolabs, one of the most recognized antibody service providers, can apply different starting antibodies, crosslinking reagents, and conjugation strategies to generate different qualified antibody-antibody conjugates, such as IgG-IgG bsAbs, F(ab’)2, and F(ab’)3 bsAbs to satisfy the specific research needs.

The synthesis of IgG-IgG bsAbs is based on the amino-reactive reagents that target lysine side-chains. Meanwhile, the crosslinkers used to conjugate IgG-IgG are usually hetero-bifunctional. In contrast to the generation of IgG-IgG bsAbs, F(ab’)2 and F(ab’)3 bsAbs are usually formed depending on homo-bifunctional reagents.

Antibody-Peptide Conjugates

Besides antibodies, the functional portions of bispecific molecules targeting antigens also include some small drugs or peptides. Antibody-peptide conjugates are chemically programmed novel pharmaceuticals that use small molecules as the navigator rather than the traditional mAbs.

These small molecules grant bsAb conjugates not only high affinity but also easy access to various cells, making antibody-peptides conjugates excellent therapeutic agents to manufacture.

Antibody-Functionality Conjugates

Chemical conjugation also allows using crosslinkers that have reactive groups to conjugate the target antibody. For instance, ScFv1-PEG-scFv2 bsAb from Creative Biolabs has three reactive groups, including two scFvs targeting two different antigens and a cross-linker containing PEG. Additional reactive groups, including fluorophores, simulating peptides, PEG, siRNA, and cytotoxic drugs are likely to enhance in vivo pharmacokinetics/pharmacodynamics (PK/PD) profile or the targeted mechanism of action.

Different from antibody-peptide conjugates, antibody-functionality conjugate retains the reactivity of antibody moieties and the property of additional functionalities rather than simply using antibody portions as carriers.

Summary

Generating bispecific antibody conjugates mainly depends on what materials and methods are used, and the strategies of DNA engineering and chemically crosslinking take a significant part in bsAb conjugate generation.

As researchers hold an optimistic attitude toward bsAbs in the application of autoimmune diseases, inflammatory diseases, cancer, etc., large-scale generation and purity should be the core task for biotechnology companies. Creative Biolabs, as a leading expert for bispecific antibody development and production, takes advantage of advanced techniques and comprehensive platforms and is making efforts to streamline and qualify bsAb conjugate construction and production. Find more information at https://www.creative-biolabs.com/bsAb/.

Being uncomfortable by those repetitive thoughts. These if exceed a limit, hinder our daily activities. This is a call for serious action. Before that let’s understand this.

What is Obsessive-Compulsive Disorder?

According to WHO, obsessive-compulsive disorder is characterized by unreasonable thoughts and fears (obsessions) that lead to compulsive behaviours. That means, some thoughts that often centres around the themes such as a fear of germs or the need to arrange objects in a specific manner or lack of sense of security, leads to compulsive behaviour like washing hands too often or checking the door repeatedly.

General factors that trigger OCD?

Stressful life events
Environmental Changes
Hormonal imbalances
Genetic factors

Acknowledgement of the problem

First, it is very important to identify the causes underlying and the factors that trigger the condition in order to overcome them. The more one tries to ignore or get rid of bothersome thoughts or urges, they keep coming back. This leads to more ritualistic behaviour(any repetitive psychomotor activity like hair pulling, handwashing performed by a person to relieve anxiety) — the vicious cycle of OCD.

OCD is not age-specific. Two percent of the worldwide population struggle with intrusive thoughts and compulsive behaviour and according to the World Health Organization, anxiety disorders, like OCD, are more prevalent in developed countries than in developing countries. Nevertheless, seeking help has made them feel better and function well at school, work, and home. It is usually advised for people suffering from obsessive-compulsive disorder(OCD) to consult a qualified mental health professional but certain self-help strategies can help an individual cope with the OCD symptoms right now!

What can you do? (SELF HELP)

Becoming Aware of One’s Thoughts.
It is crucial to become aware of an intrusive thought without forcibly trying to stop it. The first step in this process can be simply identifying the thought and putting a pause to the need of performing the compulsive action.

Developing Self Identity.
“You are not your thoughts”

People suffering from OCD might feel their thoughts overpowering them. These thoughts become an obsession and cause worry and distress and are mostly against the person’s core values and beliefs.

Handling Shame and Guilt.
Embarrassment, self-hatred, and guilt are the terms OCD patients can often relate to.

But once they are themselves aware of their thoughts without letting them take over and realize that they do not have to identify with them, it becomes easier to deal with such self-loathing.

Practising Mindfulness.
Being mindful of distressing or disturbing thoughts may act as a form of exposure to feared obsessions, similar to a hydrophobic person, learning to swim to lessen the fear.

Practising Relaxation Techniques.
Relaxing is a natural and effective anti-anxiety treatment that helps to control OCD symptoms by re-focusing your mind when obsessive thoughts and compulsions arise.

Deep breathing, exercising, progressive muscle relaxation, and meditation all help you relax. The benefits of these techniques can last for hours. When you practice them each day, your overall feelings of stress may go down. Stress is often a trigger for OCD symptoms.

If you too encounter such problems then you need to have a call or meet the specialist. Therapies can include CBT, support groups, aversion therapy, rational emotive behaviour therapy, medication, etc., or even combinations of two or more that can put a check on the thoughts and behaviour.